The clinical significance of B-cell maturation antigen as a therapeutic target and biomarker.
Sanchez E, Tanenbaum EJ, Patil S, Li M, Soof CM, Vidisheva A, Waterman GN, Hekmati T, Tang G, Wang CS, Chen H, Berenson J.
Expert Rev Mol Diagn. 2018 Apr;18(4):319-329


The Role of B-Cell Maturation Antigen in the Biology and Management of, and as a Potential Therapeutic Target in, Multiple Myeloma.
Sanchez E, Smith EJ, Yashar MA, Patil S, Li M, Porter AL, Tanenbaum EJ, Schlossberg RE, Soof CM, Hekmati T, Tang G, Wang CS, Chen H, Berenson JR.
Target Oncol. 2018 Feb;13(1):39-47


Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients.
Ghermezi M, Li M, Vardanyan S, Harutyunyan NM, Gottlieb J, Berenson A, Spektor TM, Andreu-Vieyra C, Petraki S, Sanchez E, Udd K, Wang CS, Swift RA, Chen H, Berenson JR.
Haematologica. 2017 Apr;102(4):785-795.


Effects of the Gamma Secretase Inhibitors (GSI) Dapt (GSI-IX) and LSN424354 on Gene Expression and Shedding of Bcma from Multiple Myeloma and Chronic Lymphocytic Leukemia Tumor Cells
Haiming Chen, Mingjie Li, Eric Sanchez, Camilia Soof, Saurabh Patil, Kyle Udd, Mizi Zhou, Tara Hekmati, Emily Y Wang, Edward J Tanenbaum, Remy Schlossberg, Moryel A Yashar, Cathy S Wang, George Y Tang and James R Berenson
Blood 2017 130:5390;


Soluble B-Cell Maturation Antigen Mediates Tumor-Induced Immune Deficiency in Multiple Myeloma.
Sanchez E, Gillespie A, Tang G, Ferros M, Harutyunyan NM, Vardanyan S, Gottlieb J, Li M, Wang CS, Chen H, Berenson JR .
Clin Cancer Res. 2016 Jul 1;22(13):3383-97.


Gene Expression of Gamma Secretase (GS) Complex-Related Proteins, the Enzyme That Sheds B-Cell Maturation Antigen (BCMA), Among Patients with Multiple Myeloma (MM) and Effects of the GS Inhibitor LSN424354 on Solubilized Bcma in MM and Chronic Lymphocytic Leukemia
Haiming Chen, Mingjie Li, Eric Sanchez, Cathy S Wang, Kyle A Udd, Camilia M Soof, Christian E Casas, Jessica Wang, Jasmin Cao, Kevin DeCorso, Tara Hekmati, George Tang and James R. Berenson
Blood 2016 128:5641;


Increased Alternative Macrophage-2 (M2) Polarization with Trib1 Gene over Expression in Myeloma Patients with Progressive Disease and Jak2 Inhibitors Reduce M2 Polarization
Haiming Chen, Mingjie Li, Eric Sanchez, Abigail Gillespie, Cathy Wang, Tiffany Lee, Suzie Vardanyan, Jason Nosrati, Jasmin Cao, Michael Zahab, Puja Mehta, Gigi Garzio, George Tang and James R. Berenson
Blood 2015 126:1011;


Anti-myeloma activity by the combination of the JAK2 inhibitor ruxolitinib with lenalidomide and corticosteroids.
Haiming Chen, Eric Sanchez, Mingjie Li, Cathy Wang, Abby Gillespie, Anna Shvartsur, Suzie Vardanyan, Nika M Harutyunyan, Gigi Garzio, George Tang, Benjamin Bonavida and James R. Berenson
Blood 2014 124:2114;


Serum B-cell maturation antigen is elevated in multiple myeloma and correlates with disease status and survival.
Sanchez E, Li M, Kitto A, Li J, Wang CS, Kirk DT, Yellin O, Nichols CM, Dreyer MP, Ahles CP, Robinson A, Madden E, Waterman GN, Swift RA, Bonavida B, Boccia R, Vescio RA, Crowley J, Chen H, Berenson JR.
Br J Haematol. 2012 Sep;158(6):727-38